Source: @norml @WeedConnection
Posted By: norml@weedconnection.com
media :: news - Tue, 07 Apr 2015 04:20:21 PST
Poll: 55 Percent of Likely California Voters Say Marijuana Should Be Legal
San Francisco, CA: Fifty-five percent of likely California voters believe that "the use of marijuana should be legal," according to the results of a statewide PPIC poll released last week. The percentage in favor of legalization is the highest level of support ever recorded in the history of the statewide poll.
African Americans (69 percent), Whites (64 percent), Democrats (63 percent), and Independents (57 percent) were most likely to express support for legalizing the plant's use while Republicans (44 percent), Latinos (42 percent), and Asians (39 percent) were most likely to oppose the policy change.
Among those respondents who acknowledge having tried cannabis, 74 percent supported legalization. Among respondents who had never tried cannabis, 63 percent favored keeping it illegal.
The poll possesses a margin of error of +/- 4.7 percent.
California is one of several states in 2016 where voters will likely decide the issue of regulating marijuana by ballot measure. The issue is also anticipated to be before voters next November in Arizona, Maine, Massachusetts, Michigan, Missouri, and Nevada.
Study: Plant-Derived Cannabinoid Extract More Efficacious Than Isolated Compound
Jerusalem, Israel: The administration of plant-derived cannabidiol (CBD) extracts provide greater efficacy in the treatment of pain and inflammation than does the use of a purified CBD alternative, according to preclinical data published online ahead of print in the journal Pharmacology & Pharmacy.
Investigators at the Hebrew University, Institute for Drug Research assessed the anti-inflammatory and anti-nociceptive activities of plant-derived CBD extracts in animals. Researchers reported that extracts derived from a CBD-dominant strain of cannabis provided a wider therapeutic window than did the administration of a purified form of CBD provided by a German pharmaceutical company. Authors concluded that the administration of plant-derived extracts is "superior" to the use of synthetic CBD in the treatment of certain inflammatory diseases.
"Our findings [show] that CBD in the presence of other plant constituents improve the dose-response," authors reported. "The higher efficiency of plant extract might be explained by additive or synergistic interactions between CBD and minor phytocannabinoids or non-cannabinoids presented in the extracts."
They concluded: "A lot of research has been made to isolate and characterize isolated single constituents of traditional herbal medicine to find their rationale for therapeutic uses. However, our data together with those of others provide (legitimacy) to introduce a new generation of phytopharmaceuticals to treat diseases that have hitherto been treated using synthetic drugs alone."
Full text of the study, "Overcoming the bell-shaped dose-response of cannabidiol using cannabis extract enriched in cannabidiol," appears online @ https://www.scirp.org/Journal/PaperInformation.aspx?PaperID=53912
Study: CBD Administration Enhances Skeletal Healing
Jerusalem, Israel: The administration of the non-psychotropic cannabinoid cannabidiol (CBD) leads to improvement in bone fracture healing, according to preclinical data published online ahead of print in the Journal of Bone and Mineral Research.
Investigators at the Hebrew University Bone Laboratory assessed the ability of CBD administration to promote healing in rats with mid-femoral fractures. Researchers reported, "CBD markedly enhanced the biomechanical properties of the healing femora after 8 weeks."
Authors also evaluated the administration of THC and CBD together, but reported that this combined preparation was "not advantageous" over CBD alone.
They concluded: "CBD alone is sufficiently effective in enhancing fracture healing. ... Multiple experimental and clinical trials have portrayed CBD as a safe agent suggesting further studies in humans to assess its usefulness for improving fracture healing."
Researchers have previously acknowledged that endogenous cannabinoids stimulate bone formation and inhibit bone loss, potentially paving the way for the future use of cannabinoid drugs for combating osteoporosis.
Full text of the study, "Cannabidiol, a major non-psychotropic cannabis constituent enhances fracture healing," appears in the Journal of Bone and Mineral Research.
Study: Parkinson's Patients Report Subjective Relief From Cannabis
Aurora, CO: Patients with Parkinson's self-report cannabis to be a highly efficacious alternative medicine in the treatment of the disease, according to survey data published online ahead of print in the journal Evidence-Based Complimentary and Alternative Medicine.
Investigators reported that cannabis use remains comparatively uncommon among patients with Parkinson's disease. However, those respondents who acknowledged using the plant rated it as one of the "most effective" alternative treatment therapies available.
"Cannabis was rarely used in our population but users reported high efficacy, mainly for non-motor symptoms," authors concluded.
Clinical data has previously reported that inhaled cannabis is associated with significant improvement in PD-related pain and tremor, among other symptoms.
Full text of the study, "Self-reported efficacy of cannabis and other complimentary medicine modalities by Parkinson's disease patients in Colorado," appears in the journal Evidence-Based Complimentary and Alternative Medicine.
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